Relative role of heme nitrosylation and β-cysteine 93 nitrosation in the transport and metabolism of nitric oxide by hemoglobin in the human circulation

To quantify the reactions of nitric oxide (NO) with hemoglobin under physiological conditions and to test models of NO transport on hemoglobin, we have developed an assay to measure NO–hemoglobin reaction products in normal volunteers, under basal conditions and during NO inhalation. NO inhalation m...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Gladwin, Mark T., Ognibene, Frederick P., Pannell, Lewis K., Nichols, James S., Pease-Fye, Margaret E., Shelhamer, James H., Schechter, Alan N.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.180155397
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