JunB protects β-cells from lipotoxicity via the XBP1–AKT pathway

Diets rich in saturated fats may contribute to the loss of pancreatic β-cells in type 2 diabetes. JunB, a member of the activating protein 1 (AP-1) transcription factor family, promotes β-cell survival and mediates part of the beneficial effects of GLP-1 agonists. In this study we interrogated the m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cunha, D A, Gurzov, E N, Naamane, N, Ortis, F, Cardozo, A K, Bugliani, M, Marchetti, P, Eizirik, D L, Cnop, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085537/
https://ncbi.nlm.nih.gov/pubmed/24786832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.53
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados