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JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells
Cytokines contribute to pancreatic β-cell apoptosis in type 1 diabetes (T1D) by modulation of β-cell gene expression networks. The transcription factor Activator Protein-1 (AP-1) is a key regulator of inflammation and apoptosis. We presently evaluated the function of the AP-1 subunit JunB in cytokin...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516602/ https://ncbi.nlm.nih.gov/pubmed/18716665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003030 |
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