Phosphorylation of Serine 106 in Asef2 Regulates Cell Migration and Adhesion Turnover

[Image: see text] Asef2, a 652-amino acid protein, is a guanine nucleotide exchange factor (GEF) that regulates cell migration and other processes via activation of Rho family GTPases, including Rac. Binding of the tumor suppressor adenomatous polyposis coli (APC) to Asef2 is known to induce its GEF...

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Main Authors: Evans, J. Corey, Hines, Kelly M., Forsythe, Jay G., Erdogan, Begum, Shi, Mingjian, Hill, Salisha, Rose, Kristie L., McLean, John A., Webb, Donna J.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2014
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084842/
https://ncbi.nlm.nih.gov/pubmed/24874604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr5001384
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