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Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis

Cancer-associated fibroblasts (CAFs) are major components of the surrounding stroma of carcinomas that emerge in the tumor microenvironment as a result of signals derived from the cancer cells. Biochemical cross-talk between cancer cells and CAFs as well as mechanical remodeling of the stromal extra...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Erdogan, Begum, Webb, Donna J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371349/
https://ncbi.nlm.nih.gov/pubmed/28202677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160387
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