In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts

Here we integrated multiphoton laser scanning microscopy and the registration of second harmonic generation images of collagen fibers to overcome difficulties in tracking stromal cell-matrix interactions for several days in live mice. We show that the matrix-modifying hormone relaxin increased tumor...

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Main Authors: Perentes, Jean Y, McKee, Trevor D, Ley, Carsten D, Mathiew, Hannah, Dawson, Michelle, Padera, Timothy P, Munn, Lance L, Jain, Rakesh K, Boucher, Yves
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877598/
https://ncbi.nlm.nih.gov/pubmed/19151720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1295
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