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Collagen content and extracellular matrix cause cytoskeletal remodelling in pancreatic fibroblasts

In many solid tumours a desmoplastic reaction takes place, which results in tumour tissue stiffening due to the extensive production of extracellular matrix (ECM) proteins, such as collagen, by stromal cells, mainly fibroblasts (FBs) and cancer-associated fibroblasts (CAFs). In this study, we invest...

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Bibliografski detalji
Izdano u:J R Soc Interface
Glavni autori: Stylianou, Andreas, Gkretsi, Vasiliki, Louca, Maria, Zacharia, Lefteris C., Stylianopoulos, Triantafyllos
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544883/
https://ncbi.nlm.nih.gov/pubmed/31113335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2019.0226
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