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Collagen content and extracellular matrix cause cytoskeletal remodelling in pancreatic fibroblasts

In many solid tumours a desmoplastic reaction takes place, which results in tumour tissue stiffening due to the extensive production of extracellular matrix (ECM) proteins, such as collagen, by stromal cells, mainly fibroblasts (FBs) and cancer-associated fibroblasts (CAFs). In this study, we invest...

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Bibliografische gegevens
Gepubliceerd in:J R Soc Interface
Hoofdauteurs: Stylianou, Andreas, Gkretsi, Vasiliki, Louca, Maria, Zacharia, Lefteris C., Stylianopoulos, Triantafyllos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544883/
https://ncbi.nlm.nih.gov/pubmed/31113335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2019.0226
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