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Collagen content and extracellular matrix cause cytoskeletal remodelling in pancreatic fibroblasts
In many solid tumours a desmoplastic reaction takes place, which results in tumour tissue stiffening due to the extensive production of extracellular matrix (ECM) proteins, such as collagen, by stromal cells, mainly fibroblasts (FBs) and cancer-associated fibroblasts (CAFs). In this study, we invest...
Gardado en:
| Publicado en: | J R Soc Interface |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Royal Society
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6544883/ https://ncbi.nlm.nih.gov/pubmed/31113335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2019.0226 |
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