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Transforming Growth Factor-β modulates Pancreatic Cancer Associated Fibroblasts cell shape, stiffness and invasion

BACKGROUND: Tumor microenvironment consists of the extracellular matrix (ECM), stromal cells, such as fibroblasts-FBs and cancer associated fibroblasts-CAFs, and a myriad of soluble factors. In many tumor types, including pancreatic tumors, the interplay between stromal cells and the other tumor mic...

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Publicat a:Biochim Biophys Acta
Autors principals: Stylianou, Andreas, Gkretsi, Vasiliki, Stylianopoulos, Triantafyllos
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957271/
https://ncbi.nlm.nih.gov/pubmed/29477748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2018.02.009
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