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Vasodilator-Stimulated Phosphoprotein (VASP) depletion from breast cancer MDA-MB-231 cells inhibits tumor spheroid invasion through downregulation of Migfilin, β-catenin and urokinase-plasminogen activator (uPA)

A hallmark of cancer cells is their ability to invade surrounding tissues and form metastases. Cell-extracellular matrix (ECM)-adhesion proteins are crucial in metastasis, connecting tumor ECM with actin cytoskeleton thus enabling cells to respond to mechanical cues. Vasodilator-stimulated phosphopr...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Gkretsi, Vasiliki, Stylianou, Andreas, Stylianopoulos, Triantafyllos
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349498/
https://ncbi.nlm.nih.gov/pubmed/28209486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2017.02.019
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