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Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis

Metastasis is a multistep process in which tumor extracellular matrix (ECM) and cancer cell cytoskeleton interactions are pivotal. ECM is connected, through integrins, to the cell’s adhesome at cell–ECM adhesion sites and through them to the actin cytoskeleton and various downstream signaling pathwa...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Gkretsi, Vasiliki, Stylianopoulos, Triantafyllos
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945811/
https://ncbi.nlm.nih.gov/pubmed/29780748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00145
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