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Fibroblast growth factor-2 regulates human cardiac myofibroblast-mediated extracellular matrix remodeling
BACKGROUND: Tissue fibrosis and chamber remodeling is a hallmark of the failing heart and the final common pathway for heart failure of diverse etiologies. Sustained elevation of pro-fibrotic cytokine transforming growth factor-beta1 (TGFβ1) induces cardiac myofibroblast-mediated fibrosis and progre...
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4438633/ https://ncbi.nlm.nih.gov/pubmed/25948488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0510-4 |
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