Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury

Coronary heart disease is a leading cause of death. Tissue remodeling and fibrosis results in cardiac pump dysfunction and ischemic heart failure. Cardiac fibroblasts may rebuild damaged tissues when prompted by suitable environmental cues. Here, we use acellular biologic extracellular matrix scaffo...

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Publicado en:Sci Rep
Autores principales: Svystonyuk, Daniyil A., Mewhort, Holly E. M., Hassanabad, Ali Fatehi, Heydari, Bobak, Mikami, Yoko, Turnbull, Jeannine D., Teng, Guoqi, Belke, Darrell D., Wagner, Karl T., Tarraf, Samar A., DiMartino, Elena S., White, James A., Flewitt, Jacqueline A., Cheung, Matthew, Guzzardi, David G., Kang, Sean, Fedak, Paul W. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289874/
https://ncbi.nlm.nih.gov/pubmed/32528051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66327-9
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