Phosphorylation of Serine 106 in Asef2 Regulates Cell Migration and Adhesion Turnover

[Image: see text] Asef2, a 652-amino acid protein, is a guanine nucleotide exchange factor (GEF) that regulates cell migration and other processes via activation of Rho family GTPases, including Rac. Binding of the tumor suppressor adenomatous polyposis coli (APC) to Asef2 is known to induce its GEF...

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Detalhes bibliográficos
Main Authors: Evans, J. Corey, Hines, Kelly M., Forsythe, Jay G., Erdogan, Begum, Shi, Mingjian, Hill, Salisha, Rose, Kristie L., McLean, John A., Webb, Donna J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084842/
https://ncbi.nlm.nih.gov/pubmed/24874604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr5001384
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