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The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration

Asef2 is a recently identified Rho-family guanine nucleotide exchange factor (GEF) that has been implicated in the modulation of actin, but its function in cell migration and adhesion dynamics is not well understood. In this study, we show that Asef2 is an important regulator of cell migration and a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bristow, Jeanne M., Sellers, Meredith H., Majumdar, Devi, Anderson, Bridget, Hu, Lan, Webb, Donna J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Company of Biologists 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787464/
https://ncbi.nlm.nih.gov/pubmed/19934221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.053728
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