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The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration

Asef2 is a recently identified Rho-family guanine nucleotide exchange factor (GEF) that has been implicated in the modulation of actin, but its function in cell migration and adhesion dynamics is not well understood. In this study, we show that Asef2 is an important regulator of cell migration and a...

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Bibliografische gegevens
Hoofdauteurs: Bristow, Jeanne M., Sellers, Meredith H., Majumdar, Devi, Anderson, Bridget, Hu, Lan, Webb, Donna J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Company of Biologists 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787464/
https://ncbi.nlm.nih.gov/pubmed/19934221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.053728
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