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The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration

Asef2 is a recently identified Rho-family guanine nucleotide exchange factor (GEF) that has been implicated in the modulation of actin, but its function in cell migration and adhesion dynamics is not well understood. In this study, we show that Asef2 is an important regulator of cell migration and a...

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Detalhes bibliográficos
Main Authors: Bristow, Jeanne M., Sellers, Meredith H., Majumdar, Devi, Anderson, Bridget, Hu, Lan, Webb, Donna J.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787464/
https://ncbi.nlm.nih.gov/pubmed/19934221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.053728
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