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Activation of Rac by Asef2 promotes myosin II-dependent contractility to inhibit cell migration on type I collagen
Non-muscle myosin II (MyoII) contractility is central to the regulation of numerous cellular processes, including migration. Rho is a well-characterized modulator of actomyosin contractility, but the function of other GTPases, such as Rac, in regulating contractility is currently not well understood...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3860307/ https://ncbi.nlm.nih.gov/pubmed/24144700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.131060 |
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