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α5β1 integrin trafficking and Rac activation are regulated by APPL1 in a Rab5-dependent manner to inhibit cell migration
Cell migration is a tightly coordinated process that requires the spatiotemporal regulation of many molecular components. Because adaptor proteins can serve as integrators of cellular events, they are being increasingly studied as regulators of cell migration. The adaptor protein containing a plecks...
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| Published in: | J Cell Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Company of Biologists Ltd
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897716/ https://ncbi.nlm.nih.gov/pubmed/29361527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.207019 |
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