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Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion
Rab5 is a small GTPase that regulates early endosome trafficking and other cellular processes, including cell adhesion and migration. Specifically, Rab5 promotes Rac1 activation and cancer cell migration, but little is known about the upstream regulators of Rab5. We have previously shown that the sc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074264/ https://ncbi.nlm.nih.gov/pubmed/24659799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.141689 |
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