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Novel Regulation of Integrin Trafficking by Rab11-FIP5 in Aggressive Prostate Cancer

The laminin-binding integrins, α3β1 and α6β1, are needed for tumor metastasis and their surface expression is regulated by endocytic recycling. β1 integrins share the Rab11 recycling machinery but the trafficking of α3β1 and α6β1 are distinct by an unknown mechanism. Using a mouse PDX tumor model co...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Das, Lipsa, Gard, Jaime M.C., Prekeris, Rytis, Nagle, Raymond B., Morrissey, Colm, Knudsen, Beatrice S., Miranti, Cindy K., Cress, Anne E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369592/
https://ncbi.nlm.nih.gov/pubmed/29759989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0589
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