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Effectiveness of a novel immunogenic nanoparticle platform for Toxoplasma peptide vaccine in HLA transgenic mice

We created and produced a novel self-assembling nanoparticle platform for delivery of peptide epitopes that induces CD8(+) and CD4(+)T cells that are protective against T. gondii infection. These self-assembling polypeptide nanoparticles (SAPNs) are composed of linear peptide (LP) monomers which con...

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Détails bibliographiques
Auteurs principaux: Bissati, Kamal El, Zhou, Ying, Dasgupta, Debleena, Cobb, Drew, Dubey, Jitender P., Burkhard, Peter, Lanar, David E., McLeod, Rima
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084734/
https://ncbi.nlm.nih.gov/pubmed/24736000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.03.092
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