Expression, purification and re folding of a self-assembling protein nanoparticle (SAPN) malaria vaccine

There are many ways to present antigens to the immune system. We have used a repetitive antigen display technology that relies on the self-assembly of 60 protein chains into a spherical self-assembling protein nanoparticle (SAPN) to develop a vaccine against Plasmodium falciparum malaria. The protei...

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Hlavní autoři: Guo, Qin, Dasgupta, Debleena, Doll, Tais A.P.F., Burkhard, Peter, Lanar, David E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733095/
https://ncbi.nlm.nih.gov/pubmed/23548672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.03.025
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