Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine

BACKGROUND: A lack of defined correlates of immunity for malaria, combined with the inability to induce long-lived sterile immune responses in a human host, demonstrate a need for improved understanding of potentially protective immune mechanisms for enhanced vaccine efficacy. Protective sterile imm...

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Detalhes bibliográficos
Main Authors: McCoy, Margaret E, Golden, Hannah E, Doll, Tais APF, Yang, Yongkun, Kaba, Stephen A, Burkhard, Peter, Lanar, David E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765086/
https://ncbi.nlm.nih.gov/pubmed/23607541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-136
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