Carregant...

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

We have examined the effects of commonly used chemotherapeutic agents on human colon cancer cell lines in which the p53 pathway has been specifically disrupted by targeted homologous recombination. We found that p53 had profound effects on drug responses, and these effects varied dramatically depend...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Bunz, Fred, Hwang, Paul M., Torrance, Chris, Waldman, Todd, Zhang, Yonggang, Dillehay, Larry, Williams, Jerry, Lengauer, Christoph, Kinzler, Kenneth W., Vogelstein, Bert
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC408422/
https://ncbi.nlm.nih.gov/pubmed/10430607
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!