Lataa...
Single Mutations in Tau Modulate the Populations of Fibril Conformers through Seed Selection
Seeded conversion of tau monomers into fibrils is a central step in the progression of tau pathology in Alzheimer’s disease and other neurodegenerative disorders. Self-assembly is mediated by the microtubule binding repeats in tau of which either three or four are present, depending on the protein i...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083751/ https://ncbi.nlm.nih.gov/pubmed/24453187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201308473 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|