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Fracture and Growth Are Competing Forces Determining the Fate of Conformers in Tau Fibril Populations
Tau fibrils are pathological aggregates that can transfer between neurons and then recruit soluble Tau monomers by template-assisted conversion. The propagation of different fibril polymorphs is thought to be a contributing factor to phenotypic diversity in Alzheimer disease and other Tauopathies. W...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933275/ https://ncbi.nlm.nih.gov/pubmed/27080260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715557 |
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