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Cross-seeding and Conformational Selection between Three- and Four-repeat Human Tau Proteins
In Alzheimer's disease and frontotemporal dementias, the microtubule-associated protein Tau forms intracellular paired helical filaments. The filaments can form not only by the full-length human Tau protein, but also by the three repeated (K19) or four repeated (K18) Tau segments. However, of i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340261/ https://ncbi.nlm.nih.gov/pubmed/22393063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340794 |
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