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Three- and Four-repeat Tau Coassemble into Heterogeneous Filaments: AN IMPLICATION FOR ALZHEIMER DISEASE
Tau filaments are the pathological hallmark of numerous neurodegenerative diseases including Alzheimer disease, Pick disease, and progressive supranuclear palsy. In the adult human brain, six isoforms are expressed that differ by the presence or absence of the second of four semiconserved repeats. A...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988394/ https://ncbi.nlm.nih.gov/pubmed/20921227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185728 |
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