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Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments
Tauopathies are defined by assembly of the microtubule associated protein tau into filamentous tangles and classified by the predominant tau isoform within these aggregates. The major isoforms are determined by alternative mRNA splicing of exon 10 generating tau with three (3R) or four (4R) ∼32 amin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876030/ https://ncbi.nlm.nih.gov/pubmed/20520830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010810 |
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