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Toll-like receptor 4 signaling contributes to paclitaxel-induced peripheral neuropathy

This paper tests the contribution of the toll-like receptors (TLRs), TLR4 in particular, in the initiation and maintenance of paclitaxel-related chemotherapy-induced peripheral neuropathy (CIPN). TLR4 and its immediate down-stream signaling molecules MyD88 and TRIF were increased in dorsal root gang...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Yan, Zhang, Haijun, Zhang, Hongmei, Kosturakis, Alyssa K., Jawad, Abdul Basit, Dougherty, Patrick M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083500/
https://ncbi.nlm.nih.gov/pubmed/24755282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2014.04.001
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