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A graphical method to compare the in vivo binding potential of PET radioligands in the absence of a reference region: application to [(11)C]PBR28 and [(18)F]PBR111 for TSPO imaging
Positron emission tomography (PET) radioligands for a reversible central nervous system (CNS) demand a high specific to nonspecific signal characterized by the binding potential (BP(ND)). The quantification of BP(ND) requires the determination of the nondisplaceable binding usually derived from a re...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083379/ https://ncbi.nlm.nih.gov/pubmed/24736889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.65 |
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