Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study

Positron emission tomography (PET) targeting the 18 kDa translocator protein (TSPO) is used to quantify neuroinflammation. Translocator protein is expressed throughout the brain, and therefore a classical reference region approach cannot be used to estimate binding potential (BP(ND)). Here, we used...

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Detalhes bibliográficos
Main Authors: Owen, David R, Guo, Qi, Kalk, Nicola J, Colasanti, Alessandro, Kalogiannopoulou, Dimitra, Dimber, Rahul, Lewis, Yvonne L, Libri, Vincenzo, Barletta, Julien, Ramada-Magalhaes, Joaquim, Kamalakaran, Aruloly, Nutt, David J, Passchier, Jan, Matthews, Paul M, Gunn, Roger N, Rabiner, Eugenii A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050243/
https://ncbi.nlm.nih.gov/pubmed/24643083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.46
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