An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28

[(11)C]PBR28 binds the 18-kDa Translocator Protein (TSPO) and is used in positron emission tomography (PET) to detect microglial activation. However, quantitative interpretations of signal are confounded by large interindividual variability in binding affinity, which displays a trimodal distribution...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Owen, David R, Yeo, Astrid J, Gunn, Roger N, Song, Kijoung, Wadsworth, Graham, Lewis, Andrew, Rhodes, Chris, Pulford, David J, Bennacef, Idriss, Parker, Christine A, StJean, Pamela L, Cardon, Lon R, Mooser, Vincent E, Matthews, Paul M, Rabiner, Eugenii A, Rubio, Justin P
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2012
Θέματα:
Rapid Communication
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323305/
https://ncbi.nlm.nih.gov/pubmed/22008728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.147
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια