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The Mutate-and-Map Protocol for Inferring Base Pairs in Structured RNA

Chemical mapping is a widespread technique for structural analysis of nucleic acids in which a molecule’s reactivity to different probes is quantified at single nucleotide resolution and used to constrain structural modeling. This experimental framework has been extensively revisited in the past dec...

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Autors principals: Cordero, Pablo, Kladwang, Wipapat, VanLang, Christopher C., Das, Rhiju
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080707/
https://ncbi.nlm.nih.gov/pubmed/24136598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-667-2_4
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