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Understanding the errors of SHAPE-directed RNA structure modeling
Single-nucleotide-resolution chemical mapping for structured RNA is being rapidly advanced by new chemistries, faster readouts, and coupling to computational algorithms. Recent tests have shown that selective 2´-hydroxyl acylation by primer extension (SHAPE) can give near-zero error rates (0–2%) in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172344/ https://ncbi.nlm.nih.gov/pubmed/21842868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200524n |
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