Discovery of a Dicer-Independent, Cell-Type Dependent Alternate Targeting Sequence Generator: Implications in Gene Silencing & Pooled RNAi Screens

There is an acceptance that plasmid-based delivery of interfering RNA always generates the intended targeting sequences in cells, making it as specific as its synthetic counterpart. However, recent studies have reported on cellular inefficiencies of the former, especially in light of emerging gene d...

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Detaylı Bibliyografya
Asıl Yazarlar: Bhinder, Bhavneet, Shum, David, Li, Mu, Ibáñez, Glorymar, Vlassov, Alexander V., Magdaleno, Susan, Djaballah, Hakim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079264/
https://ncbi.nlm.nih.gov/pubmed/24987961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100676
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