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A simple method for analyzing actives in random RNAi screens: introducing the “H Score” for hit nomination & gene prioritization

Due to the numerous challenges in hit identification from random RNAi screening, we have examined current practices with a discovery of a variety of methodologies employed and published in many reports; majority of them, unfortunately, do not address the minimum associated criteria for hit nominatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bhinder, Bhavneet, Djaballah, Hakim
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678258/
https://ncbi.nlm.nih.gov/pubmed/22934950
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