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Systematic analysis of RNAi reports identifies dismal commonality at gene-level & reveals an unprecedented enrichment in pooled shRNA screens

RNA interference (RNAi) has opened promising avenues to better understand gene function. Though many RNAi screens report on the identification of genes, very few, if any, have been further studied and validated. Data discrepancy is emerging as one of RNAi main pitfalls. We reasoned that a systematic...

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Библиографические подробности
Главные авторы: Bhinder, Bhavneet, Djaballah, Hakim
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885821/
https://ncbi.nlm.nih.gov/pubmed/23848309
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