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Plasmid-based shRNA lentiviral particle production for RNAi applications

Lentiviral vectors have become mainstream gene transfer vehicles for their ability to delivery and integrate into host cells. In RNA interference (RNAi) applications, lentiviral constructs constitutively express dsRNA molecules usually as short hairpin RNA (shRNA) enabling long-term gene silencing a...

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Bibliografiske detaljer
Main Authors: Shum, David, Djaballah, Hakim
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170048/
https://ncbi.nlm.nih.gov/pubmed/24939963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057114539390
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