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Plasmid-based shRNA lentiviral particle production for RNAi applications

Lentiviral vectors have become mainstream gene transfer vehicles for their ability to delivery and integrate into host cells. In RNA interference (RNAi) applications, lentiviral constructs constitutively express dsRNA molecules usually as short hairpin RNA (shRNA) enabling long-term gene silencing a...

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Détails bibliographiques
Auteurs principaux: Shum, David, Djaballah, Hakim
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170048/
https://ncbi.nlm.nih.gov/pubmed/24939963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057114539390
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