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Plasmid-based shRNA lentiviral particle production for RNAi applications
Lentiviral vectors have become mainstream gene transfer vehicles for their ability to delivery and integrate into host cells. In RNA interference (RNAi) applications, lentiviral constructs constitutively express dsRNA molecules usually as short hairpin RNA (shRNA) enabling long-term gene silencing a...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4170048/ https://ncbi.nlm.nih.gov/pubmed/24939963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057114539390 |
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