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Comparison of Effects of Different Statins on Growth and Steroidogenesis of Rat Ovarian Theca-Interstitial Cells

Statins are competitive inhibitors of 3-hydroxy-3-methyl-glutaryl-CoA reductase, the rate-limiting enzyme of the cellular production of cholesterol and other products of the mevalonate pathway. Statins exert hepatic and extrahepatic effects, modulating the function of various tissues and organs, inc...

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Autori principali: Sokalska, Anna, Stanley, Scott D., Villanueva, Jesus A., Ortega, Israel, Duleba, Antoni J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for the Study of Reproduction, Inc. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076410/
https://ncbi.nlm.nih.gov/pubmed/24389875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.113.114843
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