Resveratrol potentiates effects of simvastatin on inhibition of rat ovarian theca-interstitial cells steroidogenesis

BACKGROUND: Polycystic ovary syndrome (PCOS) is characterized by ovarian enlargement, hyperplastic theca compartment and increased androgen production due to, at least in part, excessive expression of several key genes involved in steroidogenesis. Previously, our group has demonstrated that simvasta...

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Detalhes bibliográficos
Main Authors: Ortega, Israel, Villanueva, Jesus A, Wong, Donna H, Cress, Amanda B, Sokalska, Anna, Stanley, Scott D, Duleba, Antoni J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940290/
https://ncbi.nlm.nih.gov/pubmed/24524197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-7-21
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