Resveratrol Reduces Steroidogenesis in Rat Ovarian Theca-Interstitial Cells: The Role of Inhibition of Akt/PKB Signaling Pathway

Polycystic ovary syndrome is characterized by theca-interstitial hyperplasia and increased expression of steroidogenic genes, leading to excessive androgen production. Resveratrol, a natural polyphenol, promotes apoptosis and reduces rat theca-interstitial cell growth, in part by inhibiting the meva...

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Detalhes bibliográficos
Main Authors: Ortega, Israel, Villanueva, Jesus A., Wong, Donna H., Cress, Amanda B., Sokalska, Anna, Stanley, Scott D., Duleba, Antoni J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Reproduction-Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404354/
https://ncbi.nlm.nih.gov/pubmed/22719052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1385
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