Resveratrol potentiates effects of simvastatin on inhibition of rat ovarian theca-interstitial cells steroidogenesis

BACKGROUND: Polycystic ovary syndrome (PCOS) is characterized by ovarian enlargement, hyperplastic theca compartment and increased androgen production due to, at least in part, excessive expression of several key genes involved in steroidogenesis. Previously, our group has demonstrated that simvasta...

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Autores principales: Ortega, Israel, Villanueva, Jesus A, Wong, Donna H, Cress, Amanda B, Sokalska, Anna, Stanley, Scott D, Duleba, Antoni J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940290/
https://ncbi.nlm.nih.gov/pubmed/24524197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-7-21
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