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Role of Isoprenylation in Simvastatin-Induced Inhibition of Ovarian Theca-Interstitial Growth in the Rat

Statins are competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, a rate-limiting step of the mevalonate pathway. The pleiotropic effects of statins may be due to inhibition of cholesterol synthesis, as well as decreased availability of several biologically important intermediat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rzepczynska, Izabela J., Piotrowski, Piotr C., Wong, Donna H., Cress, Amanda B., Villanueva, Jesus, Duleba, Antoni J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for the Study of Reproduction, Inc. 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770018/
https://ncbi.nlm.nih.gov/pubmed/19571257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.078667
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