Statins Inhibit Growth of Human Theca-Interstitial Cells in PCOS and Non-PCOS Tissues Independently of Cholesterol Availability

Context: Polycystic ovary syndrome (PCOS) is associated with ovarian enlargement, prominent theca-interstitial hyperplasia, and excessive androgen production. Recent clinical trials have demonstrated that statins, 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors, decrease androgen levels in wome...

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Autori principali: Sokalska, Anna, Piotrowski, Piotr C., Rzepczynska, Izabela J., Cress, Amanda, Duleba, Antoni J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999973/
https://ncbi.nlm.nih.gov/pubmed/20826585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-0770
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