Loading...

Replicative Stress and the FHIT Gene: Roles in Tumor Suppression, Genome Stability and Prevention of Carcinogenesis

The fragile FHIT gene, encompassing the chromosomal fragile site FRA3B, is an early target of DNA damage in precancerous cells. While vulnerable to DNA damage itself, FHIT protein expression is essential to protect from DNA damage-induced cancer initiation and progression by modulating genome stabil...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Karras, Jenna R., Paisie, Carolyn A., Huebner, Kay
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074825/
https://ncbi.nlm.nih.gov/pubmed/24901304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers6021208
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!