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The FHIT gene product: tumor suppressor and genome “caretaker”

The FHIT gene at FRA3B is one of the earliest and most frequently altered genes in the majority of human cancers. It was recently discovered that the FHIT gene is not the most fragile locus in epithelial cells, the cell of origin for most Fhit-negative cancers, eroding support for past claims that d...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Waters, Catherine E., Saldivar, Joshua C., Hosseini, Seyed Ali, Huebner, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Basel 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233150/
https://ncbi.nlm.nih.gov/pubmed/25283145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1722-0
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